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Examination of proinflammatory and anti-inflammatory cytokines Proinflammatory cytokines (IL-6, TNF- , and IL-1 ) and inflammatory cytokine (COX2) were determined in serum following the manufacturers protocols of purchased ELISA kits 35

2 Specifically, abnormalities in methylation, including methylation metabolites such as methionine, S-adenosyl-L-methionine (SAM) and S-adenosyl-L-homocysteine (SAH) are present in this population

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The latter report suggests that lipid membrane fragments and distorted organelles, together with a non-fibrillar form of Syn, are the main structural components of LBs and that they do not contain fibrillar Syn aggregates